What do you want to do with the boat? Even for a sport boat that is a big hull for 6S - you'll need quite a few amps to keep it on step so run time will be reduced. Most guys running boats that size use 8S or 10S and set up for lower amp draws. With larger boats, using volts to get the required power is a much better idea because it is easier on the ESC and motor, and it gives much more run time.
I agree with Ray, unless you absolutely have to go with a huge hull you'd be better off with a smaller boat. My 33" Titan 40 runs great on 4S with a Castle 240, with a racing setup it runs 50 mph for a one mile heat of under 2 minutes - never ran it longer but judging by the capacity used up I could safely run for ~4 minutes with my 9000mAh packs as long as I could control the heat buildup.
You don't need a Neu motor for a sport boat - although there is certainly nothing wrong with one for that use. A Feigao 11XL or 12XL will give speeds near 40 mph on 4S propped to run for 5-7 minutes or more (depending on your battery capacity of course). You can use a Hydra 120 just fine - although I am always in favor of getting the most ESC you can afford. Remember too that run time and amp draw has a lot to do with how you run the model - keep it on step with wide turns and you'll run longer with less heat. Constantly accelerating and slowing down with sharp turns will burn up a lot of battery capacity, giving shorter run times and higher heat buildup.
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